For over three decades industrial and academic Screening Laboratories have taken advantage of innovations in liquid handling automation and signal detection technology to screen large collections of chemical entities against a variety of biological targets. A modern HTS laboratory can generate hundreds of thousands (even millions) of data points daily. Biological targets can range from simple receptor binding to complex image analyses of live cells on robotic microscope stages. Providing a common platform for processing this diverse data is a major goal of ScreenAble.

Screening can be very expensive and resource intensive to perform at HTS scales. Since the only output from these efforts is data, it is important that this data is robustly collected, thoroughly analyzed for quality and importantly, securely stored in relational databases. All production transactions should be logged and the resultant data routinely backed up. ScreenAble provides both Inventory and Results laboratory information management systems (LIMS) for these purposes. Additionally, it offers numerous utilities specifically designed to assist screeners in providing carefully reviewed assay data of the highest quality to their internal and external customers.

The ScreenAble calculators are fast and efficient. SingleRun screens of around one hundred 384-well plates are processed in seconds and ready for review. Multiple Graphical devices, each containing dozens of pages, are easily displayed with moderate amounts of hardware. Combined with local caching of business tables, these features of ScreenAble provide a robust and responsive interface capable of the most demanding enterprise performance.